Cinnarizine – Antihistamine – Active Pharmaceutical Ingredient

Whenever human body faces allergic mediums like pollen, dirt, scents and so on, the immune system immediately reacts to provide a solution to the allergy. Thus protein molecules called Histamine is produced which act against these foreign allergens. Unfortunately, the same histamine when released in higher quantities in the mast cells they lead to severe allergies. The individuals may encounter health conditions related to nose, lungs and eyes. Cinnarizine, Fexofenadine HCL, etc. are active pharmaceutical ingredients that are used for antihistamine drugs that help in the reduction of the ill effects of Histamine. Cinnarizine has many good qualities that make it the most available option as an API for antihistamines. In addition, It is also known to reduce the imbalanced effects created by the brain due to many reasons.


Cinnarizine is derived from an organic compound named Piperazine. It is a medical derivative used as a calcium channel blocker and antihistamine. Sometimes cinnarizine is prescribed for the treatment of cerebral apoplexy and other cerebral conditions. It acts on the H1 receptors to prevent in the interaction between histamine and the receptors thereby preventing the effects of the protein molecule.





The British Royal Navy declared that Cinnarizine products are the most used by the sailors to prevent sea sickness. It is prescribed to treat conditions like vomiting, nausea, vertigo, motion sickness, Cogan’s syndrome, etc. This API is among the few that has any beneficial effect in the treatment of conditions like Tinnitus and Vertigo. Further, it has a complete metabolic rate dissolving without leaving any prints behind.


Use of cinnarizine more than the prescribed limit may induce coma and long term effects. It is not suitable for woman giving milk to their children. Other than these all the side effects can be prevented with the use of the medicine as prescribed by the doctor.

Leave A Comment